Acylated Pyrimidines

Example Definitions of "Acylated Pyrimidines"
Acylated Pyrimidines. A derivative of a uridine nucleoside or nucleotide or a derivative of a cytidine nucleoside or nucleotide in which an acyl substituent derived from a carboxylic acid is attached to one or more of the free hydroxyl groups of the ribose moiety of the nucleoside with an ester linkage and/or where such a substituent is attached to the amine substituent of the pyrimidine ring of cytidine, with an amide linkage. Such acyl substituents are derived from carboxylic acids which include, but are not... limited to, compounds selected from the group consisting of a fatty acid, an amino acid, nicotinic acid, dicarboxylic acids, lactic acid, p-aminobenzoic acid and orotic acid. A compound is included in "Acylated Pyrimidines" based on its chemical structure, regardless of the manner in which it is made., By way of example and not limitation, Acylated Pyrimidines include, but are not limited to 2',3',5'-tri-O-acetyluridine, 2'-O-propanoyluridine, N4-acetylcytidine, 2'-O-acetyl-3'-O-ethoxyuridine, uridine 2'-O-malonate, and 2',3'-diacetyluridine-5'-monophosphate. By way of example and not limitation, Acylated Pyrimidines exclude uridine, cytidine, acyl derivatives of 6-carboxycytidine, 2'-O-carboxypropyluridine, 3'-O-acetoxyethyluridine, and uridine-5'-monophosphate. View More
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