Founders Stock

Founders Stock. Shall mean all shares of Common Stock held by Founder, excluding shares of Common Stock which have been (a) registered under the Securities Act pursuant to an effective registration statement filed thereunder and disposed of in accordance with the registration statement covering them or (b) publicly sold pursuant to Rule 144 under the Securities Act.

Founders Stock. Means shares of Common Stock held by any Founder or Founder's Transferee. -2-

Founders Stock. Means the 3,400,000 shares of Common Stock to be owned by the Founders upon consummation of the transactions contemplated by Section 1.01 and Section 1.04 of the Purchase Agreement.

Founders Stock. Shall have the meaning ascribed thereto in the introductory paragraph to this Agreement and shall also include any securities issued upon exchange, adjustment or transfer of any such shares, the certificates for which are required by the provisions of Section 2 hereof to bear the legend set forth in such Section.

Founders Stock. Shall mean the Common Stock now owned or hereafter acquired by Leonard T. Guarente, Cynthia Kenyon, Cindy Bayley, Louis Kunkel and Annibale Puca.

Founders Stock. All shares of the capital stock of the Company and owned beneficially or of record by a Founder, or any such shares of which a Founder acquires beneficial or record ownership after the date hereof, excluding shares of preferred stock of the Company that are purchased by a Founder for the same price per share paid by unaffiliated third parties.

Founders Stock. The Common Stock acquired by the Founders pursuant to the Founder's Stock Purchase Agreements with the Company; provided, however, that, for the purposes of Sections 5.1, 5.2 and 5.3, Founders' Stock shall not include any Common Stock subject to a right of repurchase in favor of the Company pursuant to a Founder's Stock Purchase Agreement between the Company and a Founder unless, until, and to the extent that such right of repurchase has lapsed