Phase 1Phase 2Phase 3 and Phase 4

Phase 1Phase 2Phase 3 and Phase 4. Means Phase 1, Phase 2, Phase 3 and Phase 4 clinical trials, respectively, in each case as prescribed by the U.S. Food and Drug Administration or any successor entity (the "FDA"), and agencies of other governments of other countries having similar jurisdiction over the development, manufacturing and marketing of pharmaceuticals.