Principal Investor

Principal Investor. Means each of Brightstar Associates LLC ("Brightstar"), New Leaf Ventures III, L.P. and any Affiliates (collectively, "New Leaf") and SV Life Sciences Fund VI, L.P., SV Life Sciences Fund VI Strategic Partners, LP, and any Affiliates ("SVLS"), Viking Global Opportunities Intermediate LP, DRAGSA 14 LLC and any Affiliates (collectively, "Viking"), and Redmile Capital Fund, LP, Redmile Capital Offshore Fund, Ltd., Redmile Capital Offshore Fund II, Ltd., Redmile Special Opportunities Fund, Ltd.,... Redmile Biopharma Investments I, L.P., and any Affiliates ("Redmile") and any Person to which the rights under this Agreement may be assigned by Brightstar, New Leaf, SVLS, Viking, and Redmile as the case may be, pursuant to clause (i) or (ii) of Section 3.1 and which holds at least 480,250 Common Shares (subject to appropriate adjustment for share splits, share dividends, combinations, and other recapitalizations). View More

Principal Investor. The meaning given to such term in the Principal Investor Agreement

Principal Investor. Any Investor holding at least 600,000 shares of Registrable Securities (equitably adjusted for any stock splits, subdivisions, stock dividends, changes, combinations or the like) and any Wellington Investor

Principal Investor. Each of Clayton, Dubilier & Rice Fund VII, L.P. and KKR 2006 Fund L.P.