TOPICAL

TOPICAL. Shall mean delivery to the skin in a vehicle such as a cream, an ointment, or equivalent vehicle, whereby the therapeutic action is via a local effect on the skin, and excluding (i) other local delivery modalities to the skin, such as transdermal, in which the primary therapeutic purpose is to have a systemic effect, (ii) other local delivery modalities such as ophthalmic, oral-local to the GI tract, or to tissues or organs other than the skin, and... (iii) drug-device combinations that provide local delivery to tissues or organs other than the skin; View More