Major Investor

Major Investor. Means any Investor that, individually or together with such Investor's Affiliates, holds at least 1,066,666 shares of Registrable Securities (in each case, as adjusted for any stock split, stock dividend, combination, or other recapitalization or reclassification effected after the date hereof).

Major Investor. Any Investor that, individually or together with such Investor's Affiliates, holds at least 2,000,000 shares of Registrable Securities (as adjusted for any stock split, stock dividend, combination, or other recapitalization or reclassification effected after the date hereof). Notwithstanding the foregoing, Blackwell Partners LLC—Series A shall also be considered a "Major Investor".

Major Investor. Means (i) LAV, (ii) the holder of the Viking Convertible Note, and (iii) any Investor that, individually or together with such Investor's Affiliates, holds at least 400,000 shares of Registrable Securities (as adjusted for any stock split, stock dividend, combination, or other recapitalization or reclassification effected after the date hereof).

Major Investor. Means any Investor who has purchased at least $10,000,000 of Preferred Stock from the Company, each Person to whom any of the rights of any such Investor are assigned pursuant to Section 6.1, each Person who hereafter purchases at least $10,000,000 of Preferred Stock from the Company and becomes an Investor pursuant to Section 6.10 and any one of them, as the context may require; provided, however, that Taiho Ventures, LLC ("Taiho"), Citadel Multi-Strategy Equities Master Fund Ltd.... ("Surveyor"), Bay City Capital GF Xinde International Life Sciences USD Fund, L.P. ("Bay City"), and any Person to whom any of the rights of Taiho, Surveyor or Bay City, respectively, are assigned pursuant to Section 6.1 shall each be deemed to be a Major Investor for so long as such Investor holds at least fifteen percent (15%) of the shares of Series B Preferred Stock purchased by such Investor pursuant to the terms of the Series B Preferred Stock Purchase Agreement, dated as of November 5, 2018 (the "Series B Purchase Agreement"); provided, further, that any such Person shall cease to be considered a "Major Investor" for purposes of this Agreement if such Person ceases to be an Investor. View More

Major Investor. Means (i) any Investor that, individually or together with such Investor's Affiliates, holds at least 500,000 shares of Registrable Securities (as adjusted for any stock split, stock dividend, combination, or other recapitalization or reclassification effected after the date hereof), (ii) each Fidelity Investor that holds any Registrable Securities and (iii) Hillhouse, so long as it holds any Registrable Securities.

Major Investor. Any Investor that, individually or together with such Investor's Affiliates, holds at least (a) 2,400,000 shares of Registrable Securities or (b) at least 2,200,000 shares of Series D Preferred Stock (in each case as adjusted for any stock split, stock dividend, combination, or other recapitalization or reclassification effected after the date hereof)

Major Investor. Means any (i) any Fidelity Investor, (ii) any Flagship Investor, (iii) any Gurnet Point Investor, and (v) any Investor that, individually or together with such Investor's Affiliates, holds at least 350,000 shares of Registrable Securities (as adjusted for any stock split, stock dividend, combination, or other recapitalization or reclassification effected after the date hereof). For purposes of this definition, "Gurnet Point Investor" shall mean Gurnet Point L.P. and its Affiliates.

Major Investor. Means any Investor that, individually or together with such Investor's Affiliates, holds at least 11,140,819 shares of Registrable Securities then outstanding (as adjusted for any stock split, stock dividend, combination, or other recapitalization or reclassification effected after the date hereof); provided that in the event that Blackwell Partners LLC – Series A ceases to be an Affiliate of RA Capital Healthcare Fund, L.P., (i) RA Capital Healthcare Fund, L.P. shall remain a Major Investor so... long as it holds at least 9,243,538 shares of Registrable Securities then outstanding (as adjusted for any stock split, stock dividend, combination, or other recapitalization or reclassification effected after the date hereof), and (ii) Blackwell Partners LLC – Series A shall immediately and automatically cease to be a Major Investor. View More

Major Investor. Means any Investor that, individually or together with such Investor's Affiliates, holds at least 2,500,000 shares of Registrable Securities (as adjusted for any stock split, stock dividend, combination, or other recapitalization or reclassification effected after the date hereof); provided, that, notwithstanding the foregoing, Twin Prime Investments LLC shall be a Major Investor.

Major Investor. Means any Investor that, individually or together with such Investor's Affiliates, holds at least 10% of the then outstanding shares of Registrable Securities (as adjusted for any stock split, stock dividend, combination, or other recapitalization or reclassification effected after the date hereof) who is not a Competitor.